In this session, we'll explore possible interaction patterns and how they affect accessibility in non-traditional environments, like mixed reality or wearables, as we transition from graphical user interfaces to organic user interfaces. We'll discuss the kinds of interfaces needed to enable and empower next-generation applications--from augmented and virtual reality to IoT to wearables--taking a deeper look at natural language, gestures, computer vision and even thought, as the next generation of user interaction.